How do you clean honey comb shades?

Grab a plain white wash cloth to clean with – colors on the towel might bleed onto the shade. Dampen the towel with warm water and sprinkle a gentle detergent (same used on clothes is fine) on the towel – no colored or harsh cleaners.

Lightly scrub the cell shade to remove any dirt/stains

Try using the brush attachment of your vacuum.

I've tried vacuuming mine and it just sucks them into a crinkle. Try a large dry paint brush. I keep one in every room. For baseboards, blinds, dry spills. It's like a little tiny broom but thicker.

Depending on the material used, I have put them in the tub with a bit of soap and bleach. Then rinse, and hang up to dry partially folded so the creasing shows.

I did a test on one blind to remove heavy smoke stains. They looked new when I was done.