What is the best way to save a paintbrush with hardened paint?
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https://www.wikihow.com/Revive-Paintbrushes-With-Vinegar
You could use paint remover but it would probably be less expensive to buy a new brush and take care of it next time. I don't think that you will find a pantry staples concoction that will cut hardened latex paint.
Throw it in the garbage!
Soak your paintbrush in straight white distilled vinegar. I have not tried this, only read about it, so I can't guarantee the results
This is a good start. Hope it helps.
http://www.apartmenttherapy.com/quick-tip-40-how-to-remove-dried-paint-from-paint-brushes-154477
If acrylic or watercolor, soak in warm soapy water. If oil, there’s a brush cleaner solvent in any craft or art store. (Michael’s, AC Moore, Jerry’s Artarama.com)
Does this harm the brush bristles?