How to kill poison oak and poison ivy for good?

They are spread by wind, wildlife and people. Best you can do is suit up, dig it out and treat the area. They have a chemical you can paint on but I have never used it.

Poison ivy and poison oak are both perennials so this is hard to do. The only way I know of would be to dig it out roots and all (at great personal risk). Whatever you do don’t burn it. The fumes contain the poison and if you breathe it in it is a very serious situation.

wish I knew. that is the devil's weed

Here is an article that might help you - https://www.wikihow.com/Kill-Poison-Oak

I've heard of people not only spraying with a weed killer for woody vines, but also INJECTING the herbicide into the trunk, and spreading runners; Birds love the berries .. so if you live close to a wooded area infested with it, you'll be fighting it forever ...

Goats,rent them . Goats love poison ivy and will eat it all,killing . They might be pricey to rent but it works.

Hot...hot water

3 cups white vinegar

1/2 cup table salt

1 tablespoon liquid detergent or soap (I use Dawn) for stick-to-itiveness.

Directions

1. Mix vinegar and salt until the salt is completely dissolved. Stir in liquid dish soap, and pour into a spray bottle.
2. Spray onto the green growing leaves of the plants.
3. Wait a week, then repeat on any survivors. Best time to apply: during a dry spell.

Repeat as necessary.