Do you have a photo you could share here? That would help for ideas. :)
A classic look is to stain the top and paint the bottom. What kind of dresser do you have?
If you want to paint it, I recommend using an oil-based countertop paint for the tabletop. This will be a surface you can wipe over and over and that will perform well over time. I believe the one I've used before was a rust-oleum product.