I am gluing some colored glass gems onto a glass window..

B sure 2 let e6000 dry f0r 24hrs b4 sprayn w/anything. S0unds like u hv a gr8 pr0ject g0ing 0n, will b beautiful

The Krylon may yellow badly w sun exposure. Talk to some one at a good hardware store. I don't think it's a good idea. The glass will hold up fine, as well as the pane. The glue is protected by the glass beads. Don't spray it.

I didn't seal my glass beaded outdoor lights and they still look great.

Don't spray them with anything. Glass is easy to clean and sparkle; if you coat them dirt will stick and the coating will eventually discolor spoiling the look. I used glass blobs in my shower - they look like bubbles. I used E6000 to attach them. They make a new polymer grout that is translucent so the light shines through it letting the glass sparkle. It is very expensive however. I would only use it where there is constant water spraying on the glass.

I have done several GOG and they hung outside year around. No need to spray. As others have said the E6000 will hold just fine and it is much easier to clean windows when they need it. Just a little windex and a paper towel.

I'm looking to do something similar indoors. Can you post a photo of the finished product?

I've made multiple lights for out in my yard using glass beads glued with E6000 glue on both plastic and glass containers. They've held up for years, even with NE Pennsylvania winters. I never sprayed anything over them. So, I don't really think the spray will benefit the appearance or endurance. E6000 glue is amazingly durable. Good luck!